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Emergency Medicine Clinic of North America, 28, 149-161. Toxicology: Pearls and pitfalls in the use of antidotes.

Haddad and Winchester's clinical management of poisoning and drug overdose (Fourth ed.). Emergency Medicine Australasia, 24, 225-238. Review article: Management of cyanide poisoning. Pediatric cyanide poisoning by fire smoke inhalation: A european expert consensus. Mintegi, S., Clerigue, N., Tipo, V., Ponticiello, E., Lonati, D., Burillo-Putze, G., & Delvau, N. Cyanokit, hydroxycobalamin package insert. Critical Reviews in Toxicology, 39 (7), 541-552. Goldfrank's toxicologic emergencies (Tenth ed.). Forensic Science International, 223, 10-12. Case report: Antidote treatment for cyanide poisoning with hydroxocobalamin causes bright pink discolouration and chemical-analytical interferences. Tucson, Arizona: The University of Arizona College of Medicine.īrunel, C., Widmer, C., Augsburger, M., Dussy, F., & Fracasso, T. (Ed.), AHLS advanced hazmat life support, provider manual (4th ed.). Quebec, Canada: Centre antipoison du Quebec.īorron, S. Antidotes en toxicologie d'urgence (3rd ed.). Please contact the Ontario Poison Centre about all poison exposure patients to ensure they receive the most current evidence-based care available.Bailey, B., Blais, R., Gaudreault, P., Gosselin, S., & Laliberte, M. (2009). It should also be noted that more than one antidote may be listed for a particular intoxication. It should be noted that as medical toxicology knowledge changes, antidotes may change. The list is compiled from the literature referenced below. The Ontario Poison Centre cannot make specific stocking recommendations as it is difficult to predict an individual hospital's needs, especially in the event of a large environmental poisoning. The guidelines indicate when stock should be available for immediate use and which can be available within 60 minutes. This initial dose listed is the amount typically required to treat an average 100 kg patient in the first eight hours. It should be noted that this does not replace the usual symptomatic and supportive care necessary for the treatment of a poisoned patient. Attached below is a guideline for the stocking of recommended antidotes in acute care settings.